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Interstitial LDR (low dose rate)
brachytherapy of the prostate represents a prostate cancer treatment
with significantly reduced side effects and less surgical risk. LDR
brachytherapy is the implantation
of small, weak radio-active radiation sources (so-called seeds) directly
into the cancerous tissue. As these seeds are only about 0.8 mm in diameter
and 4.5 mm in length,
the implantation is performed by injection through needles.
The seeds develop their effect directly in the cancerous tissue, only a
small dose burden is exposed to adjacent organs. In long term studies the
healing rate was found to be comparable to the surgical removal of the
prostate. Currently more than 100,000 cases of prostate cancer are treated
per year worldwide by the implantation of seeds.
The LDR brachytherapy treatment planning software PSID
(Permanent Seed Implant
Dosimetry) for
ultrasound guided radiation therapy of prostate cancer developed by sonoTECH
since 1999 is used for treatment planning at numerous sites in Europe and
beyond. The use of advanced 3D visualization techniques allows an overview
of the planning results at unsurpassed speed and flexibility. |
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The planning is based on sequence of ultrasound images which
are loaded into the
program either by the integrated real time frame grabber, through a network
(DICOM TCP/IP) or from file. After contouring the organs with the mouse, the
program calculates the optimum seed distribution depending on the desired dose
levels in a few seconds. Alternatively a partially edited seed distribution
may be completed automatically or the complete seed distribution may be
placed manually. Isodoses are updated immediately.
PSID will automatically calculate the dose volume
histogram, the differential dose distribution, the natural dose volume
histogram, the needle loading plan and
other parameters required to evaluate the quality of the dose distribution.
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Based on the organ contours PSID will calculate
3D views
from any desired viewing angle. The organ structures may be rotated in any
direction. Select the organs to be displayed with a mouse click. Choose
whether the seeds and / or needles should also be displayed. Naturally,
selected isodose surfaces will be displayed in 3D as well, if desired.
Slice the 3D structures in any direction to see where the seeds are located,
for example. Choose the transparency / opacity of each organs you look right through the surface and see what is behind. The 3D
color-coded surface dose feature allows easy detection of hot spots at organ surfaces.
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The needle loading plan is the essential for seed placement.
The plan describes how to load the needles with seeds, where to position the
needles and how deep the needles are to be inserted into the prostate. If it
is desired to place the seeds at intermediate positions this will also be
displayed.
Manual and Auto placement support
single seeds as well as strands.
Ease of operation and quick response times in combination with reliable
seed auto placement and seed finding features allow performing the complete
planning job in an unsurpassed short time period.
Please contact us if you would like to receive more
information on our products. We will be happy to arrange a presentation,
even at your site. |
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Summary of PSID Version 4.5 Features:
- Image acquisition
with frame grabber, files, DICOM network, etc.
- Up to 20 different image formats
supported: DICOM, BMP, JPEG, TIFF, GIF, PNG, etc.
- DICOM 3.0 TCP/IP network
interface
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Co-registration (i.e. planning based on images from different imaging
modalities) of two image sequences with up to 127 images per sequence.
- Algorithms and data for all common seed / strand types are included or
can easily be added by the build-in seed editor.
- Complies to the current AAPM TG-43 recommendations (Supplement to the 2004
update of the AAPM Task Group No. 43 Report) dated May 2007. Accurate point and line source modeling of the seed anisotropy is implemented.
- Easy
manual contouring of anatomical structures with the
mouse
- Interpolation of missing contours on intermediate slices
- Simple positioning of single seeds or Strands with a mouse click on
the template grid or on a finer grid
- Automatic placement results of seeds and strands are unsurpassed by
manual editing
- Interactive Online Planning during implantation based on transversal and longitudinal real live
ultrasound images (25 frames per second) even on Laptops - the exact
needle and seed positions can be used for online correction of the further
treatment
- A
manually edited incomplete partial placement of seeds and strands can be completed automatically by the incremental automatic
placement feature.
- Real-time calculation of isodoses during seed / strand positioning.
- Simultaneous application of seeds with different activities in one
study
- Immediate calculation of local dose at cursor position
- Standard template geometries and customer
templates are selectable
- Visualization of calculation results in 2D and 3D
- 3D isodoses and seed display, 3D organ surface depiction based on the
manually drawn contour
- User
definable, comprehensive report in color, consisting of more than
50 pages in
letter format including: Seed data, patient data, needle loading plan, isodoses,
doses volume histograms, histogram parameters, etc. The report can be
previewed before printing.
- Image Fusion between Ultrasound-, MR and CT images for easier contouring during
post planning
- Automatic seed detecting algorithm for post planning
based on CT-images dramatically reduces the time required to create post
plans
- 2D isodoses and seed display in sagittal and coronal direction
- The Maximum Intensity Seed Navigator is a three dimensional DRR (Digitally
Reconstructed Radigraph) that can be also used for editing the seeds.
- Seed setting and dragging in 2D even on oblique planes as well as in the DRR. The DRR can be rotated in real time.
- Simple scaling of template size and position
- User
configurable depiction of line thickness and color of contours, isodose lines,
seeds, etc.
- Multilingual operator interface in English and
German (Other languages on request).
- Needle loading display and edit feature for the selected needle
- Image Fusion between image sequences at any angle
- Conformal Index COIN
- The amount of calculation points used for the
determination of the histograms is user definable independently for screen
and report. These calculation points are distributed on a
three-dimensional hexagonal grid to achieve a homogeneous filling of the
structure.
- Cumulated, differential and Natural Dose Volume Histogram (NDVH) Natural
Prescription Dose (NPD) and Natural
Dose
Ratio (NDR) online and in the report.
- Online Vxx (Dose of Vol % of target volume), Dxx (Volume with Dose >
xx in Vol %) and Dcc (Volume Dose in cm³) Histogram parameters updated online
on the screen and printed in the report.
- CIVCO™ EXII™ stepper position encoder support for automated
acquisition of image sequences and automated tracking of transversal and
longitudinal plane in online planning mode..
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Multithreading (parallel processing) support: Increasing the execution
speed on computers with Quad Core™ processors by a factor of four.
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Licensing with local dongle or with remote dongle (floating license over a
network) allows installation on several computers.
- Intuitive operator guidance
- Build-in context sensitive online help, i.e. for
any object of the software the related chapter of the help manual appears after pressing function
key [F1].
- Developed for
Windows™
XP, Windows™ Vista™ and Windows™ 7 in Administrator and Standard
Mode.
and much, much more...
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Laptop Configuration Example
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Intel® Core™2 Duo Prozessor T8100 (2.1 GHz, 3MB L2-Cache,
800 MHz FSB)
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4096 MB 667 MHz Dual-Channel
DDR2 SDRAM
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320GB (7.200rpm) Serial ATA
Hard Drive
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Fixed Internal 8X DVD+/-RW Slot
Load Drive
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nVidia® GeForce™
8600M GS (128 Bit) 256 MB
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WXGA+-Display (1440 x 900) non
glare
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Real Time Video Frame
Grabber (PAL 50 Hz: 768 x 576 pixel / NTSC 60 Hz: 640 x 480 pixel )
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Microsoft™
Windows™ XP Professional Operating System
(Service Pack 3) or
Vista® Business SP1
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